The Extracellular Matrix


In 1975, Dr. Alfred Pischinger, Professor of Histology and Embryology at the University of Vienna, presented the results of a lifetime of research on the Extracellular Matrix. From the beginning, Dr. Pischinger understood that the origins of health were not in the individual cells of the body, but within the connective tissue matrix. His ground-breaking research proved that this Extracellular Matrix is the one continuous system in the human body which allows instantaneous communication through alterations in molecular configurations. The lymphatic system is the cellular milieu of this matrix, managing the nutrition of every cell and removal of their waste products. Disease arises as a result of dysfunction of this Matrix from heavy metal loads, effects of stress (Dr. Hans Selye, 1953 Stress and the General Adaptation Syndrome), and various noxious substances causing chronic inflammation including the chronic use of pharmaceuticals. Dr. Pischinger discovered that by normalizing the Extracellular Matrix, chronic diseases such as multiple sclerosis, ulcerative colitis, and rheumatoid arthritis became amenable to treatment.

At approximately the same time, the development of thermodynamic theory helped us realize that biological systems do not show linearity. They are highly interlinked and are subject to a balance of biological flow with constant interchange of energy and matter with their environment. Once this is understood, then all one-dimensional causal chains in biological systems can no longer claim to be scientific (F. Thomas, 1984). This truth undoes the entire thesis of all so-called "scientific" clinical research which is entirely based on one-dimensional studies known as "double blind, controlled studies."

The Extracellular Matrix (ECM) permeates the entire organism, reaches every cell, and always reacts as a single unit. Biochemically the ECM consists of a meshwork of high-polymer sugar-protein complexes. These form a molecular sieve by virtue of their shape, electrical charges, and ability to bind water. The Matrix is responsible for mechanical cohesion of tissues as well as their shock-absorbing characteristics. The fibroblasts are responsible for synthesizing the Matrix, which forms into an orderly geometric structure with "minimal surfaces". Minimal surfaces have a remarkable capability of reacting to small changes in one place, with very large changes at a great distance away (Karcher and Polthier, 1990). This is the basis of instantaneous communication throughout the entire Extracellular Matrix.

Acupuncture Points: Window on the Extracellular Matrix

In 1988, a German Histologist, Dr. H. Heine, demonstrated that the Matrix stretched from the depths of the body towards the surface in the formaccupuncture of cylinders of meshwork which enclose the perforating nerve and vascular bundles. These "Heine Cylinders" perforate the surface tissue at the Acupuncture points described by the Chinese over three thousand years ago.

Thus the acupuncture points are the precise points on the body where the Extracellular Matrix reaches the surface and where the Matrix can both receive information from the environment, and be influenced over great distances. This recent understanding gives credibility to the ancient science of acupuncture and the Chinese acupuncture meridian system.

The first confirmation of this theory focused on the acupuncture point Bladder 17 (BL 17) which is the accupuncture3Master point of the diaphragm. After stimulating BL 17, located on either side of the spinous process of the 7th thoracic vertebra, there was measurable relaxation of the diaphragm muscle, change in diaphragm contour, and increase in the amplitude of the diaphragm movement. This confirms that there is a regulatory relationship between the acupuncture point and its associated organ (in this case, the diaphragm).

Homeopathy: Rooted in the Extracellular Matrix

Extremely low energy inputs can set off spontaneous reactions in biological systems. Thus, if highly diluted, a toxin can become a healing substance (homeopathic remedy). This means that if a substance can destroy the spontaneity of biological reactions, it can also support this spontaneity. By diluting a toxin using homeopathic methods, it can be "engineered" to react with the Extracellular Matrix at the level of water and the high-polymer sugar-protein complexes (see above). At this level of molecular interaction, the energy of the toxin actually promotes healing in the Extracellular Matrix.

It is especially interesting that in the highest homeopathic potencies, the toxin has gone through a potentizing process resulting in a medication which contains none of the original toxin. Thus the most powerful homeopathic potencies contain only the energetic information stored in the sucussed water. Homeopathy is thus a medical discipline geared to stimulation and recovery of the Extracellular Matrix at the molecular level.

Note from Dr. Walkey: I have collated the above information from a single text entitled: The Extracellular Matrix and Ground Regulation: Basis for a Holistic Biological Medicine by Alfred Pischinger translated from German into English in 2007. The original references are available from this text.

Comment by Dr. Walkey: When conventional western medicine understands the principles of this book, and begins to incorporate these basic ideas into their approach towards healing, is when western medicine will abandon the corruption of the pharmaceutical industry, reevaluate longterm side effects of chronically administered prescription drugs, and begin the long unwinding of the consequences of decades of unhealthy healthcare. June 2, 2011

For a scientific explanation of homeopathy follow this link: